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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis

Fig. 3

Adhesion of pre-cultured BMMs to plastic surface. Adhesion to plastic surface was measured 36 h after seeding, and pre-cultured BMMs from controls and from CIA animals were compared (a). Data are shown as percentage of BMMs from control animals set to 100 %. Influence of stimulation with ACh and VIP on adhesion of BMMs from control and CIA animals is shown as percentage to non-stimulated macrophages (non-stimulated = dotted line) (b), and respective results for noradrenergic stimulation are shown under (c). N = 6 for control and CIA BMMs and the applied neurotransmitters at each time point. Data are expressed as mean ± standard error of the mean. *P < 0.05 neurotransmitter stimulation versus non-stimulated cells; ## P < 0.01 control cells versus CIA cells. ACh acetylcholine, BMM bone marrow-derived macrophage, CIA collagen II-induced arthritis, NA noradrenaline, VIP vasoactive intestinal peptide

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