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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of carbonic anhydrase III selected in a murine model by phage display

Fig. 6

Anti-M12 antibody detection by ELISA. Detection of anti-M12 antibodies in sera from rheumatoid arthritis (RA) patients (n = 172), healthy controls (HC) (n = 113), systemic lupus erythematosus (SLE) patients (n = 19) and ankylosing spondylitis (AS) patients (n = 13) and the respectively receiver operating characteristic (ROC) curve. a Sera from the four groups individually tested for their ability to bind to synthetic M12 peptide. Horizontal line = cut-off value; error bars show mean and standard deviation. b ROC curve constructed based on the control groups. The area under the curve (AUC), sensitivity (Se), specificity (Sp) and corresponding p-value are indicated inside the graph

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