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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Suppressed diversity of survivin splicing in active rheumatoid arthritis

Fig. 1

Survivin splice variants. Exon organisation in mRNA of human most frequent survivin splice variants, which comprise 98 % of mRNA expression from the BIRC5 gene. Splice variants were measured using the same forward primer located in the N-terminus. The reverse primers were located within exon 3 (for survivin-WT), within the inserted sequence derived from intron 2 (for survivin-2B) and within the unique sequence of exon 4 (for survivin-ΔEx3). Arrows indicate positions of PCR primers. Sequences for each primer can be found in Methods. UTR untranslated region, WT wild type

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