Skip to main content

Table 2 Effect of rituximab treatment in patients with rheumatoid arthritis

From: Suppressed diversity of survivin splicing in active rheumatoid arthritis

 

Before RTX

After RTXa

DAS28 score

5.89 ± 0.6

4.34 ± 0.7

Rheumatoid factor (IU/ml)

  

 IgG

41.5 ± 29.3

22.7 ± 19.5*

 IgM

67.2 ± 31.1

50.2 ± 38.3

 IgA

41.0 ± 38.3

25.0 ± 19.5

WBC count (×109/l)

  

 PBMCs

6.5 ± 3.1

7.8 ± 3.2

 BM

2.1 ± 1.4

2.6 ± 1.6

CD19+ (%)b

  

 PBMCs

7.7 ± 3.8

0

 BM

9.4 ± 4.3

1.3 ± 1.2

CD3+ (%)b

  

 PBMCs

45.9 ± 15.8

42.5 ± 12.9

 BM

28.0 ± 9.8

29.4 ± 16.5

  1. Values presented as mean ± standard deviation, n = 23
  2. a Samples 1–3 months after RTX treatment
  3. b From the lymphocyte population
  4. * p = 0.008
  5. p <0.0001
  6. BM bone marrow, DAS28 Disease Activity Score based on evaluation of 28 joints, PBMC peripheral blood mononuclear cells, RTX rituximab, WBC white blood cell