Position in HLA-DRB1 | Amino acid residue | Frequency | Univariable | Stepwise model (entry P = 0.05) applied separately at each position | |||
---|---|---|---|---|---|---|---|
Cases | Controls | OR | P value | OR | P value | ||
9 | E | 0.698 | 0.565 | 1.78 | 7.3×10−8 |  |  |
K | 0.011 | 0.011 | 1.03 | 0.96 | Â | Â | |
W | 0.291 | 0.424 | 0.56 | 5.8×10−8 | 0.56 | 5.85×10−8 | |
11 | D | 0.011 | 0.011 | 1.03 | 0.96 | Â | Â |
G | 0.127 | 0.142 | 0.88 | 0.38 | Â | Â | |
L | 0.060 | 0.123 | 0.46 | 3.6×10−5 | 0.64 | 0.040 | |
P | 0.104 | 0.159 | 0.63 | 0.0024 | Â | Â | |
S | 0.391 | 0.371 | 1.09 | 0.41 | 1.37 | 0.015 | |
V | 0.307 | 0.194 | 1.86 | 1.4×10−7 | 2.06 | 2.8×10−7 | |
13 | F | 0.071 | 0.141 | 0.48 | 1.7×10−5 | 0.66 | 0.038 |
G | 0.040 | 0.045 | 0.87 | 0.60 | Â | Â | |
H | 0.307 | 0.187 | 1.96 | 1.5×10−8 | 2.11 | 5.5×10−8 | |
R | 0.104 | 0.159 | 0.63 | 0.0024 | Â | Â | |
S | 0.351 | 0.325 | 1.12 | 0.28 | 1.38 | 0.014 | |
Y | 0.127 | 0.142 | 0.88 | 0.38 | Â | Â | |
33 | H | 0.307 | 0.187 | 1.96 | 1.5×10−8 | 1.96 | 1.527×10−8 |
N | 0.693 | 0.813 | 0.51 | 1.5×10−8 |  |  | |
37 | F | 0.147 | 0.161 | 0.89 | 0.39 | Â | Â |
L | 0.022 | 0.017 | 1.27 | 0.49 | Â | Â | |
N | 0.256 | 0.219 | 1.09 | 0.46 | Â | Â | |
S | 0.164 | 0.282 | 0.51 | 8.0×10−8 | 0.59 | 0.00012 | |
Y | 0.402 | 0.276 | 1.63 | 3.2×10−6 | 1.37 | 0.0055 |