Fig. 2

Esophageal biopsy cluster membership. Significance of clustering (SigClust) and consensus clustering assessed the robustness and significance of the sample clusters. a SigClust revealed two significant (p = 0.05) clusters of systemic sclerosis (SSc) patients. Biopsies from six patients demonstrated a stable inflammatory gene expression pattern. An asterisk indicates samples obtained at 6 months. The colored bars below the dendrogram indicate sample cluster membership from SigClust and consensus clustering. Additional file 10 contains the cumulative density function and delta area plots from the consensus clustering performed