Skip to main content

Advertisement

Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: The role of interleukin-1 beta in the pathophysiology of Schnitzler’s syndrome

Fig. 1

Serum concentrations of IL-6, myeloid-related protein (MRP)8/14 and S100A12, and peripheral blood mononuclear cell (PBMC)-associated IL-6 correlate with disease activity. a Serum IL-6 levels in controls, and in Schnitzler’s syndrome (SchS) patients with or without NLRP3 mosaicism during anakinra (IL-1Ra) treatment, a symptomatic episode, at several time points during a canakinumab (anti-IL-1β antibody) trial, and during relapse after canakinumab withdrawal. b IL-6 concentration in lysates of freshly isolated PBMCs from SchS patients with or without NLRP3 mosaicism. c Correlation between serum and cell-associated IL-6 concentrations in SchS patients. d Serum MRP8/14 and e S100A12 concentrations during anakinra treatment, a symptomatic episode, and 28 days after a single injection of canakinumab

Back to article page