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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Peripheral blood derived mononuclear cells enhance osteoarthritic human chondrocyte migration

Fig. 2

Chondrocyte migration experiment results (n = 4). a Scratch assay measuring the distance between the wound migration fronts in a chondrocyte monolayer and b wound closure rate in a chondrocyte monolayer scratch assay at the 3-h time point. c Representative image of xCELLigence cell migration analysis from four wells (technical replicates) with chondrocytes measured for 3 days evaluating the chemokinetic effect of peripheral blood mononuclear cells (PBMC+ in the lower chamber and PBMC# in the same chamber). Error bars represent standard deviation and cell index value is based on impedance measurements that provide quantitative information about cell migration through the pores of the membrane measured continuously with microelectrodes. d Total chondrocyte migration at day 3 in the xCELLigence assay and e xCELLigence assay comparing mesenchymal stroma cell (MSC) and chondrocyte (CHO) migration at day 3 (n = 6). f Total cartilage cell migration from tissue explant at day 28 in the xCELLigence assay. g Cartilage cell migration rate from tissue explant at day 14 in the xCELLigence assay. **p <0.001, ***p <0.0001 and ****p <0.00001

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