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Table 1 The list of gene C6orf10 related diseases, as a novel RA pleiotropic gene identified by GWAS analysis

From: Knowledge-based analysis of genetic associations of rheumatoid arthritis to inform studies searching for pleiotropic genes: a literature review and network analysis

SNPs

Population

Disease relevance

PubMed ID

rs1265777, rs574710, rs539703, rs2894249

British

RA

20018019

rs6910071, rs9391858, rs10484560, rs6910071

North American

RA

20018025, 20018077, 20018006, 21592391

rs2395148

Canadian, U.S.

PBC

19458352

rs2073048, rs28732201

European, Chinese Han

Psoriasis

19680446, 20692714

rs926070, rs2073044

Cleveland

Leukemia

20460636

rs3130320

 

SLE

21408207

rs3117103, rs7746019

European

SLE

19851445

rs7775397

 

NL

22031281

rs7758128

European

Vitiligo

21326295

rs485774

U.S., Canada

LOAD

22245343

rs498422

Chinese Han

NOA

22541561

rs2050190

Utah

CAD

22703881

DG6S398, D6S2889

Caucasians

T1D

19143811

rs9391858

British

T1D

20549515

rs3129934

European

MS

19010793

  1. GWAS genome-wide association study, RA rheumatoid arthritis, PBC primary biliary cirrhosis, Leukemia T cell large granular lymphocyte leukemia, SLE systemic lupus erythematosus, NL neonatal lupus, Vitiligo generalized vitiligo, LOAD late-onset Alzheimer disease, NOA nonobstructive azoospermia, CAD coronary artery disease, T1D diabetes mellitus, type 1, MS multiple sclerosis