Year (patients) | ESR (mm/h) | CRP (mg/dl) | 28 tender joint count | 28 swollen joint count | DAS28-ESR | CDAI | SDAI | Assessor’s global assessment (VAS, mm) |
---|---|---|---|---|---|---|---|---|
2004 | 22.3 (16.8) | 14.8 (18.9) | 4.2 (5.5) | 4.1 (4.6) | 3.9 (1.4) | 14.8 (10.9) | 16.2 (11.8) | 22.6 (16.1) |
(n = 404) | [77.7 %] | [81.2 %] | [87.4 %] | [87.4 %] | [74.3 %] | [85.0 %] | [77.2 %] | [86.6 %] |
2005 | 22.1 (17.4) | 13.6 (15.2) | 4.0 (5.5) | 3.5 (4.1) | 3.8 (1.4) | 13.5 (10.6) | 14.7 (11.5) | 19.9 (15.3) |
(n = 604) | [80.8 %] | [79.8 %] | [90.2 %] | [90.2 %] | [79.6 %] | [89.4 %] | [78.5 %] | [90.1 %] |
2006 | 22.7 (16.5) | 13.0 (13.1) | 4.8 (5.7) | 3.3 (3.7) | 4.0 (1.4) | 14.4 (10.4) | 15.5 (10.8) | 20.1 (16.1) |
(n = 620) | [76.6 %] | [78.4 %] | [90.0 %] | [90.0 %] | [75.2 %] | [87.6 %] | [76.0 %] | [88.9 %] |
2007 | 23.3 (18.7) | 14.9 (18.0) | 4.5 (5.7) | 3.3 (4.0) | 3.9 (1.4) | 13.9 (11.0) | 15.7 (11.9) | 21.0 (16.3) |
(n = 743) | [63.4 %] | [66.8 %] | [72.1 %] | [72.1 %] | [57.9 %] | [67.3 %] | [60.4 %] | [71.3 %] |
2008 | 20.9 (16.2) | 10.9 (17.4) | 3.6 (4.8) | 3.1 (3.7) | 3.6 (1.3) | 12.2 (10.0) | 13.3 (10.6) | 17.9 (15.9) |
(n = 796) | [62.8 %] | [66.7 %] | [74.9 %] | [74.9 %] | [56.0 %] | [64.1 %] | [58.7 %] | [71.4 %] |
2009 | 19.4 (15.8) | 8.4 (14.2) | 2.9 (4.6) | 2.7 (3.6) | 3.3 (1.3) | 10.8 (9.4) | 11.9 (10.1) | 17.0 (16.0) |
(n = 969) | [70.6 %] | [74.0 %] | [83.4 %] | [83.4 %] | [64.0 %] | [75.9 %] | [66.3 %] | [81.8 %] |
2010 | 19.1 (15.0) | 8.0 (12.6) | 2.5 (4.2) | 1.9 (3.1) | 3.2 (1.3) | 9.1 (8.3) | 9.8 (8.6) | 13.0 (12.7) |
(n = 1069) | [80.4 %] | [81.2 %] | [89.9 %] | [89.9 %] | [77.4 %] | [85.4 %] | [77.6 %] | [88.5 %] |
2011 | 18.2 (14.7) | 7.1 (12.0) | 1.9 (3.4) | 1.4 (2.5) | 3.0 (1.2) | 8.0 (7.4) | 8.6 (7.7) | 12.9 (13.4) |
(n = 1103) | [80.2 %] | [84.0 %] | [90.0 %] | [90.0 %] | [78.5 %] | [87.9 %] | [81.9 %] | [90.1 %] |
2012 | 18.0 (15.6) | 7.0 (13.2) | 1.5 (3.5) | 1.2 (2.5) | 2.8 (1.2) | 7.1 (7.1) | 7.8 (7.5) | 10.6 (12.6) |
(n = 1113) | [78.0 %] | [83.1 %] | [91.3 %] | [91.3 %] | [75.8 %] | [88.2 %] | [80.6 %] | [91.0 %] |
2013 | 17.2 (14.2) | 6.4 (10.6) | 1.3 (3.0) | 0.8 (1.8) | 2.7 (1.1) | 6.3 (6.1) | 7.0 (6.3) | 9.7 (11.4) |
(n = 1083) | [76.8 %] | [80.4 %] | [89.8 %] | [89.8 %] | [74.1 %] | [86.1 %] | [76.6 %] | [89.6 %] |
P valuea 2004–2013 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
P valuea 2010–2013 | 0.012 | 0.007 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |