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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Protein kinase C delta null mice exhibit structural alterations in articular surface, intra-articular and subchondral compartments

Fig. 3

Confocal microscopic analyses of calcein fluorescence revealed an enhanced bone formation in the interface between the growth plate and metaphysis in protein kinase C delta (PKC-δ)−/− mice. a, b The tibia and femur trabecular bone showed an increased fluorescence (indicated by red arrow) in the PKC-δ−/− mice (b) as compared to PKC-δ+/+ mice (a). c, d An enlargement of the tibia from panels a and b respectively. e The measurement of fluorescently labeled intensity per area (μm2) of trabecular bone from panels c and d. *p < 0.05. (Laser scanning confocal microscope: a and b, ×12.5; c and d, ×100)

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