Fig. 4

Histopathological evaluation reveals absence of uveitis in animals that had received a zymosan injection. Eyes of SKG mice were evaluated at 10 weeks or 16 weeks after zymosan injection for signs of ocular disease. The number of leukocytes within the aqueous humor of the anterior segment and within the vitreous body of the posterior segment in response to zymosan was quantified (a). Representative photographs show the anterior (b) and posterior (c) eye segments at 10 weeks after zymosan injection. A anterior, P posterior, AC anterior chamber, C cornea, Ir iris, Lb limbus, CB ciliary body, L lens, V vitreous, R retina. Statistical significance was not achieved for zymosan versus naive SKG mice of either sex at either time point. n = 17–23 mice/group or versus BALB/c controls (combined three individual experiments)