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Table 2 Changes in patient’s assessments of disease activity, pain and morning stiffness and odds ratios for an increase of at least 20 mm in visual analogue scales for these outcomes during the presence of a flare, compared to the absence of a flare (reference category)

From: Disease flares in rheumatoid arthritis are associated with joint damage progression and disability: 10-year results from the BeSt study

  Change in VASda Change in VASpain Change in VASms
  Median IQR Median IQR Median IQR
No flare A 0 −8 to 5 0 −8 to 5 0 −8 to 6
Flare A 17 3 to 40 17 3 to 35 11 0 to 29
No flare B 0 −8 to 5 0 −8 to 5 0 8 to 6
Minor flare B 7 −4 to 20 5 −4 to 18 5 −5 to 16
Major flare B 18 4 to 41 18 3 to 37 12 0 to 31
  Increase in VASdaa Increase in VASpaina Increase in VASmsa
  ORb 95 % CI ORb 95 % CI ORb 95 % CI
No flare A ref ref ref ref ref Ref
Flare A 8.47 7.30–9.83 8.35 7.20–9.69 5.63 4.84–6.55
No flare B ref ref ref ref ref Ref
Minor flare B 3.10 2.35–4.07 2.84 2.15–3.75 2.32 1.73–3.12
Major flare B 8.76 7.46–10.28 8.59 7.32–10.08 5.90 5.01–6.94
  1. aIncrease ≥20 mm from the previous VAS
  2. bAdjusted for time
  3. CI confidence interval, IQR interquartile range, OR odds ratio, ref reference category, VASda visual analogue scale of disease activity, VASpain visual analogue scale of pain, VASms visual analogue scale of morning stiffness