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Table 2 Changes in patient’s assessments of disease activity, pain and morning stiffness and odds ratios for an increase of at least 20 mm in visual analogue scales for these outcomes during the presence of a flare, compared to the absence of a flare (reference category)

From: Disease flares in rheumatoid arthritis are associated with joint damage progression and disability: 10-year results from the BeSt study

 

Change in VASda

Change in VASpain

Change in VASms

 

Median

IQR

Median

IQR

Median

IQR

No flare A

0

−8 to 5

0

−8 to 5

0

−8 to 6

Flare A

17

3 to 40

17

3 to 35

11

0 to 29

No flare B

0

−8 to 5

0

−8 to 5

0

8 to 6

Minor flare B

7

−4 to 20

5

−4 to 18

5

−5 to 16

Major flare B

18

4 to 41

18

3 to 37

12

0 to 31

 

Increase in VASdaa

Increase in VASpaina

Increase in VASmsa

 

ORb

95 % CI

ORb

95 % CI

ORb

95 % CI

No flare A

ref

ref

ref

ref

ref

Ref

Flare A

8.47

7.30–9.83

8.35

7.20–9.69

5.63

4.84–6.55

No flare B

ref

ref

ref

ref

ref

Ref

Minor flare B

3.10

2.35–4.07

2.84

2.15–3.75

2.32

1.73–3.12

Major flare B

8.76

7.46–10.28

8.59

7.32–10.08

5.90

5.01–6.94

  1. aIncrease ≥20 mm from the previous VAS
  2. bAdjusted for time
  3. CI confidence interval, IQR interquartile range, OR odds ratio, ref reference category, VASda visual analogue scale of disease activity, VASpain visual analogue scale of pain, VASms visual analogue scale of morning stiffness