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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Expression of Semaphorin 4A and its potential role in rheumatoid arthritis

Fig. 6

Semaphorin 4A (Sema4A) promotes TNF-α and IL-1β production in lipopolysaccharide (LPS)-activated THP-1. Expression (a) and secretion (b) of Sema4A were analyzed by qRT-PCR and ELISA in THP-1 after LPS stimulation. Secretion of TNF-α (c) and IL-1β (d) was determined by ELISA after recombinant human semaphorin 4A (rhSema4A), or in combination with LPS treatment. *P <0.05 (statistically significant differences)

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