Author | Feature (method) | Pain outcome | Adjustment for confounders | Association (magnitude) crude | Association (magnitude) adjusted | Association | Quality score (%) |
---|---|---|---|---|---|---|---|
Hand MRI bone marrow lesion case series | |||||||
Haugen 2014 Abstract [144] | Sum scores (0–48) for BMLs (Oslo hand OA MRI score) (C) | AUSCAN pain scale (L) | Age, sex, BMI, follow-up time | NR | β = −0.26, 95 % CI −0.55 to 0.03 | NA | High (61) |
Hand MRI bone marrow lesion cross-sectional studies | |||||||
Haugen 2012 [145] | BML (Oslo MRI hand score) (C) IPJs sum scores | AUSCAN pain scale (C) | Age, sex | NR | OR (95 % CI) 0.96 (0.82 to 1.12) | NA | High (64) |
Hand MRI osteophyte cross-sectional studies | |||||||
Haugen 2012 [145] | Osteophyte (Oslo MRI hand score) (C) IPJs sum scores | AUSCAN pain scale (C) | Age, sex | NR | OR (95 % CI) 1.04 (0.98 to 1.10) | NA | High (64) |
Hand MRI attrition cross-sectional studies | |||||||
Haugen 2012 [145] | Attrition (Oslo MRI hand score) (C) IPJs sum scores | AUSCAN pain scale (C) | Age, sex | NR | OR (95 % CI) 1.15 (0.98 to 1.34) | NA | High (64) |
Hand MRI subchondral cyst cross-sectional studies | |||||||
Haugen 2012 [145] | Cyst (Oslo MRI hand score) (C) IPJs sum scores | AUSCAN pain scale (C) | Age, sex | NR | OR (95 % CI) 0.93 (0.56 to 1.55) | NA | High (64) |
Hand scintigraphy subchondral bone cross-sectional studies | |||||||
Macfarlane 1993 [61] | Late phase isotope bone scan small joints of the hand (C) | Hand pain VAS (C) | Nil | Correlation coefficient 0.06, p = 0.304 | NR | NA | Low (57) |
Hip MRI bone marrow lesion cross-sectional studies | |||||||
Kumar 2013 [151] | Total hip semi-quantitative BML score (C) | Self-reported hip pain HOOS score (C) | Nil | NR | p correlation −0.29 (p <0.01) | A higher BML score means a lower or worse HOOS pain score | High (71) |
Maksymowych 2014 [152] | Semi-quantitative BML HIP (HOAMS) (C) | Baseline WOMAC pain (C) | Nil | p <0.001 | NR | + | High (64) |
Hip MRI subchondral cyst cross-sectional studies | |||||||
Kumar 2013 [151] | Total hip semi-quantitative subchondral cyst score (C) | Self-reported hip pain HOOS score (C) | Nil | NR | p correlation −0.37 (p <0.001) | A higher cyst score means a lower or worse HOOS pain score | High (71) |