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Table 1 Characteristics of the patients with early RA and of the healthy controls included in the study

From: Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate

 

RA patients

Healthy controls

Number

19

17

Female, (%)

5 (26.3)

6 (35.3)

Age at diagnosis, median (IQR)

61.6 (51–65)

58 (39–64)

Symptoms to MTX, median months (IQR)

6.0 (2.2–7.3)

 

RF (%)

11 (57.9)

 

ACPA (%)

11 (57.9)

 

Erosive arthritis (%)

2 (10.5)

 

Smoking (%)

8 (42.1)

 

Methylprednisolone, median mg/day (IQR)

4 (4–8)

 

Metothrexate, median mg/week (IQR)

10 (10–10)

 

CRP (mg/L), median (IQR)

  

 Baseline

15.3 (3.9–23.2)

 

 1 month

5.2 (1.2–9.4)

 

ESR, median (IQR)

  

 Baseline

28.0 (6.0–38.0)

 

 1 month

14.0 (6.5–24.0)

 

DAS28, mean ± SD

  

 Baseline

4.6 ± 1.6

 

 1 month

3.2 ± 1.5

 
  1. RA rheumatoid arthritis, IQR interquartile range, MTX methotrexate, RF rheumatoid factor, ACPA anti-citrullinated peptide antibody, CRP C-reactive protein, ESR erythrocyte sedimentation rate, DAS28 disease activity factor in 28 joints, SD standard deviation