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Table 3 Association between clinical parameters and circulating endostatin in the MCTD cohort

From: Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study

Clinical manifestations Univariable Multivariablea
Regression coefficient 95 % CI P value Regression coefficient 95 % CI P value
Pulmonary fibrosis 10.5 1.9, 19.1 .017    
% of predicted FVC − .33 −.55, −.12 .002    
% of predicted DLCO −.40 −.64, −.16 .001    
Digital ulcers 10.7 3.2, 18.2 .006 10.5 3.2, 17.8 .005
  1. MCTD mixed connective tissue disease, FVC forced vital capacity, DLCO diffusing capacity of the lungs for carbon monoxide
  2. aVariables in the final multivariable regression model: digital ulcers, age and gender