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Table 3 Association between clinical parameters and circulating endostatin in the MCTD cohort

From: Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study

Clinical manifestations

Univariable

Multivariablea

Regression coefficient

95 % CI

P value

Regression coefficient

95 % CI

P value

Pulmonary fibrosis

10.5

1.9, 19.1

.017

   

% of predicted FVC

− .33

−.55, −.12

.002

   

% of predicted DLCO

−.40

−.64, −.16

.001

   

Digital ulcers

10.7

3.2, 18.2

.006

10.5

3.2, 17.8

.005

  1. MCTD mixed connective tissue disease, FVC forced vital capacity, DLCO diffusing capacity of the lungs for carbon monoxide
  2. aVariables in the final multivariable regression model: digital ulcers, age and gender
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