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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: CDP7657, an anti-CD40L antibody lacking an Fc domain, inhibits CD40L-dependent immune responses without thrombotic complications: an in vivo study

Fig. 2

Inhibition of humoral immune response in Cynomolgus monkeys: comparison of antibody formats. Animals received a single i.v. dose of antibody or saline 2 days prior to administration of tetanus toxoid (TT); the doses were 20 mg/kg for the IgG antibodies and 40 mg/kg for the PEGylated formats (nā€‰=ā€‰6 for all groups). The IgG anti-TT titers in plasma samples were assessed from days 10 to 31

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