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Table 2 CDP7657 cross-reactivity with human and non-human primate (Cynomolgus and Rhesus monkey) CD40L

From: CDP7657, an anti-CD40L antibody lacking an Fc domain, inhibits CD40L-dependent immune responses without thrombotic complications: an in vivo study

Cell type KD (nM)
  Human Cynomolgus monkey Rhesus monkey
  Donor 1 Donor 2 Donor 1 Donor 2 Donor 1 Donor 2
PBMC 1.57 1.41 1.50 1.13 1.21 0.80
  1. PBMC peripheral blood mononuclear cell