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Table 2 CDP7657 cross-reactivity with human and non-human primate (Cynomolgus and Rhesus monkey) CD40L

From: CDP7657, an anti-CD40L antibody lacking an Fc domain, inhibits CD40L-dependent immune responses without thrombotic complications: an in vivo study

Cell type

KD (nM)

 

Human

Cynomolgus monkey

Rhesus monkey

 

Donor 1

Donor 2

Donor 1

Donor 2

Donor 1

Donor 2

PBMC

1.57

1.41

1.50

1.13

1.21

0.80

  1. PBMC peripheral blood mononuclear cell
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Arthritis Research & Therapy

ISSN: 1478-6362

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