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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate

Fig. 3

Serum concentration of ACPA and ACPA specificities. Graphs show the results of ELISA measurements of the antibody concentrations for patients being positive at baseline or at 3 months for the corresponding antibody: ACPA n = 120 (a), anti-cit-enolase (amino acids 5–21) n = 71 (b), anti-citrullinated (cit)-vimentin (vim) (amino acids 60–75) n = 67 (c), anti-cit-fibrinogen (fib) (amino acids 563–583) antibodies n = 42 (d). Horizontal lines represent median values, * p <0.05. Dotted lines delineate ELISA cutoff values for each antibody. ACPA anti-citrullinated protein antibodies, ELISA enzyme-linked immunosorbent assay

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