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Table 3 Comparison of patients with (painDETECT ≥13) and without neuropathic pain symptoms

From: Neuropathic-like pain features and cross-sectional associations in rheumatoid arthritis

  No NP NP P
  Symptoms Symptoms  
Female sex, n (%) 61 (62.2) 43 (70.5) 0.288
Age (years), mean ± SD 57.7 (10.9) 56.3 (11.0) 0.432
Education, n (%)    
 Low 22 (22.4) 15 (25.0)  
 Medium 57 (58.2) 36 (60.0)  
 High 19 (19.4) 9 (15) 0.768
Current smoking, n (%) 15 (15.3) 12 (19.7) 0.476
Current alcohol, n (%) 73 (74.5) 47 (77.0) 0.715
Disease duration (years), median (IQR) 6.0 (3.0–12.0) 6.0 (3.0–12.0) 0.912
FM, n (%) 6 (6.1) 17 (28.3) <0.001
Prescribed RA medication, n (%)    
 DMARD 58 (59.2) 37 (60.7) 0.854
 DMARD plus biologic 25 (25.5) 15 (24.6) 0.897
 Biologic 11 (11.2) 7 (11.5) 0.961
 NSAID only 3 (3.1) 2 (3.3) 1.000
Self-reported current pain medication, n (%) 37 (37.8) 44 (73.3) <0.001
Self-reported current neuropathic pain medication, n (%) 4 (4.1) 5 (8.3) 0.263
Current pain (0–10), mean ± SD 2.5 (2.2) 4.6 (2.3) <0.001
Strongest pain (0–10), mean ± SD 3.2 (2.6) 6.0 (2.3) <0.001
Average pain (0–10), mean ± SD 2.7 (2.2) 4.8 (2.1) <0.001
DAS28 (0–10), mean ± SD 2.0 (1.0) 2.3 (1.0) 0.095
ESR (mm/hour), median (IQR) 8.0 (2.5–15.0) 8.0 (5.0–17.0) 0.610
CRP (mg/l), median (IQR) 2.0 (1.0–7.0) 3.0 (2.0–8.0) 0.107
SJC (0–28), mean ± SD 0 (0–1) 0 (0–1) 0.603
TJC (0–28), mean ± SD 0 (0–1) 0 (0–2) 0.016
HAQ-DI (0–3), mean ± SD 0.5 (0.5) 1.1 (0.6) <0.001
SF-36 PCS (0–100), mean ± SD 44.9 (8.2) 36.4 (8.7) <0.001
SF-36 MCS (0–100), mean ± SD 52.7 (9.4) 46.5 (10.6) <0.001
  1. CRP C-reactive protein, DAS28 28-joint Disease Activity Score, DMARD disease-modifying antirheumatic drug, ESR erythrocyte sedimentation rate, FM fibromyalgia, HAQ-DI Health Assessment Questionnaire disability index (standard scoring), IQR interquartile range, MCS mental component summary, NP neuropathic pain, NSAID nonsteroidal anti-inflammatory drug, PCS physical component summary, RA rheumatoid arthritis, SF-36 36-item Short-Form health survey, SJC swollen joint count, TJC tender joint count