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Table 1 Human nucleus pulposus tissue sampling

From: Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells

  Pfirrmann grade II Pfirrmann grade IV P value
(n = 9) (n = 23)
Mean age (yr) 13.6 ± 1.5 39.8 ± 11.5 <0.01
Sex (male:female) 2:7 16:7 <0.01
Diseases Idiopathic scoliosis: 9 Lumbar disc herniation: 13  
Lumbar spinal stenosis: 10