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Table 3 Unadjusted rates of mACR20/50/70 and mHAQ improvement

From: Comparative effectiveness and safety of rituximab versus subsequent anti–tumor necrosis factor therapy in patients with rheumatoid arthritis with prior exposure to anti–tumor necrosis factor therapies in the United States Corrona registry

Outcome, %

Trimmed population

Stratified-matched population

Rituximab

Anti-TNF

P value

Rituximab

Anti-TNF

P value

(n = 265)

(n = 737)

(n = 205)

(n = 205)

mACR20

36.6

28.7

0.02

38.1

22.0

0.001

mACR50

21.1

17.4

0.17

21.0

13.7

0.005

mACR70

10.2

8.8

0.46

10.2

7.3

0.29

mHAQ

33.2

24.2

0.004

34.2

23.9

0.02

  1. Anti-TNF anti–tumor necrosis factor, mACR modified American College of Rheumatology criteria, mHAQ modified Health Assessment Questionnaire