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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Reanalysis of the Rituximab in ANCA-Associated Vasculitis trial identifies granulocyte subsets as a novel early marker of successful treatment

Fig. 3

Granulocyte subpopulations and treatment outcomes. a Representative bidimensional dot plot illustrating the granulocyte subpopulations identified in an automated manner. Left: Hypergranular granulocytes (definitions in Table 1). Right: Hypogranular granulocytes. FSC forward scatter, SSC side scatter. b and c Granularity Index at day 0 among patients receiving rituximab and cyclophosphamide, respectively, stratified by treatment outcome. Data distribution is shown as a notched boxplot (showing minimum, maximum, 25th percentile, median and 75th percentile). An unpaired Kruskal-Wallis rank-sum non-parametric test was used to calculate significance. WBC white blood cells

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