Bone marrow lesions can be subtyped into groups with different clinical outcomes using two magnetic resonance imaging (MRI) sequences

Table 1 Baseline participant characteristics according to the presence of any BML being present¹

	No BML	BML on T2 only	BML on T1 and T2	p value²
	N = 258	N = 9	N = 29	p value²
Age (years)	57.7 (5.2)	59.8 (7.6)	59.9 (6.0)	0.06
Gender, n (%) female	159 (62)	7 (78)	20 (69)	0.48³
BMI (kgm⁻²)	25.7 (4.1)	27.0 (4.0)	27.5 (5.5)	0.09
Baseline tibial cartilage volume (mm³)
Medial	1695 (532)	1609 (382)	1807 (554)	0.49
Lateral	2026 (648)	1994 (724)	2012 (610)	0.98

Results expressed as mean (standard deviation) or number (%)
BML bone marrow lesion, BMI body mass index
¹One participant had a BML present only on T1-weighted sequences, and was not included
² p value expressed as F test – pairwise comparisons among the unadjusted means
³Chi-square test