Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 3 Relationship between the presence of BML according to sequence at baseline and tibial cartilage volume1

From: Bone marrow lesions can be subtyped into groups with different clinical outcomes using two magnetic resonance imaging (MRI) sequences

  No BML BML in T2 only BML in T1 and T2 p value4
Baseline cartilage volume (mm3)2
 Medial compartment
  n = 273 n = 7 n = 16  
  Medial 1705 (32) 1552 (200) 1743 (133) 0.72
  Medial, adjusted2 1698 (22) 1722 (139) 1809 (95) 0.52
 Lateral compartment
  n = 278 n = 2 n = 16  
  Lateral 2014 (39) 2462 (456) 2176 (161) 0.335
  Lateral, adjusted2 2020 (28) 2356 (323) 2137 (117) 0.345
Annual change in cartilage volume (mm3)
 Medial compartment
  n = 248 n = 7 n = 15  
  Medial 22 (3) −11 (19) 42 (13) 0.07
  Medial, adjusted3 22 (3) −13 (19) 45 (14) 0.04
 Lateral compartment
  n = 254 n = 2 n = 14  
  Lateral 22 (3) 70 (36) 55 (13) 0.025
  Lateral, adjusted3 22 (3) 69 (36) 55 (14) 0.025
  1. BML bone marrow lesion
  2. 1One participant had a BML present only on T1-weighted sequences, and was not included
  3. 2Estimated marginal means (standard error of the mean, SEM) used to compare groups adjusted for baseline age, gender, body mass index (BMI)
  4. 3Estimated marginal means (SEM) used to compare groups adjusted for baseline age, gender and BMI. Annual change is expressed such that a negative value represents a gain in cartilage volume
  5. 4 p value for F test, pairwise comparisons among the estimated marginal means across all groups, except where indicated
  6. 5For lateral compartment, the comparison was between those with no BML at baseline and those with BML visible using both T1- and T2-weighted images, as n = 2 for BML visible using T2-weighted images only