Fig. 1
From: CD1a+ survivin+ dendritic cell infiltration in dermal lesions of systemic sclerosis
Immunohistochemistry (IHC) staining of XIAP, cIAP and survivin in systemic sclerosis (SSc) dermal lesions. SSc (a, c, e) and non-SSc (b, d, f) skin lesions evaluated with IHC (all stained by red, ×20). The SSc patients were designated numbers 4, 6, 7, and 12 in Table 1 (n = 4). A case of rheumatoid arthritis (RA), a case of polymyositis/dermatomyositis (PM/DM) and two cases of osteoarthritis (OA) were included among the non-SSc patients (n = 4). a, b XIAP. c, d cIAP. e, f survivin. Representative images are shown. In the dermis of SSc, many survivin-positive cells were detected (arrows)