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Table 3 Gene expression comparison between hip vs. knee OA, and intact healthy cartilage vs. cartilage with minor degeneration in controlsa

From: Overexpression of MMP13 in human osteoarthritic cartilage is associated with the SMAD-independent TGF-β signalling pathway

Gene Hip OA Knee OA p Healthy controls Controls with minor degeneration p
(n = 7) (n = 25) (n = 14) (n = 7)
TGFB1 6.40 ± 2.16 5.71 ± 2.51 0.42 3.35 ± 1.74 4.36 ± 1.89 0.20
SMAD3 2.55 ± 1.59 2.62 ± 0.76 0.56 1.84 ± 1.46 1.60 ± 1.14 1.00
MMP13 1.74 ± 2.21 0.90 ± 0.74 0.53 0.31 ± 0.53 0.41 ± 0.80 0.82
BMP2 0.15 ± 0.02 0.08 ± 0.01 0.13 1.17 ± 0.31 1.23 ± 0.46 0.65
  1. OA osteoarthritis
  2. aFigures are relative quantification (RQ) mean ± standard deviation