Table 1 Study eligibility criteria
Inclusion criteria | Exclusion criteria | |
|---|---|---|
Participants | Fibromyalgia patients (FM) or FM and a healthy population | Patients with other diseases, mixed types of patients (i.e., FM patients with other disorders), only a healthy population |
No restrictions on the number of participants and the diagnostic procedures were applied | ||
Biomarkers | Cytokines, neuropeptides and CRP | Other biomarkers |
Interventions | Non-pharmacological interventions were eligible | Mixed or blended non-pharmacological interventions, only pharmacological interventions |
Outcome | At least one biomarker (cytokine or neuropeptide or CRP) outcome | Studies in which biomarkers were used as predictors to identify the participants were excluded |
Study design | RCTs, Non-RCTs | |
Publications | Published in English, French or Spanish and as full-text articles in peer-reviewed scientific journals from January 1990 to March 2015 | Published in other languages and as reviews, case reports or letters |