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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Early treatment with hydroxychloroquine prevents the development of endothelial dysfunction in a murine model of systemic lupus erythematosus

Fig. 3

Inhibitory effects of N ω-nitro-l-arginine methyl ester (l-NAME) on acetylcholine-induced maximal relaxation at baseline and different time points in control C57BL/6 J mice (Ctrl), NZB/W F1 mice (NZ), and NZB/W F1 mice treated with hydroxychloroquine (NZ-HCQ). Each column represents the mean ± SEM of eight experiments. *P < 0.001; **P < 0.05 vs. other Ctrl groups; ***P < 0.01; P < 0.01 vs. NZ baseline; P < 0.01 vs. 18-week-old NZ; P < 0.01 vs. 24-week-old NZ. Apo apocynin

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