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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Early treatment with hydroxychloroquine prevents the development of endothelial dysfunction in a murine model of systemic lupus erythematosus

Fig. 4

Dihydroethidium (DHE) staining for detection of superoxide production. Representative DHE staining (upper panels) and quantitative analysis of the red signal (lower panels; original magnification, ×40) in mesenteric arteries from C57BL/6 J mice control mice (Ctrl) and NZB/W F1 mice (NZ) at baseline, from NZ groups without or with apocynin (Apo) or polyethylene glycol superoxide dismutase (PEG-SOD), and from NZB/W F1 mice treated with hydroxychloroquine (NZ-HCQ) at different time points. Each column represents the mean ± SEM of six experiments. *P < 0.001; P < 0.05

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