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Table 2 Histopathology

From: Early treatment with hydroxychloroquine prevents the development of endothelial dysfunction in a murine model of systemic lupus erythematosus

Age, wk

Nephritis score (mean ± SD)

P value

 

NZ

NZ-HCQ

 

12

0 ± 0

–

n.s.

18

0.4 ± 0.5

–

n.s.

24

0.75 ± 0.5

2 ± 0.5

n.s.

30

1 ± 0.9

2 ± 0.5

n.s.

36

2.8 ± 1.2

3 ± 4.6

n.s.

  1. n.s. not significant, NZ NZB/W F1 mice, NZ-HCQ NZB/W F1 mice treated with hydroxychloroquine, SD standard deviation
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Arthritis Research & Therapy

ISSN: 1478-6362

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