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Table 2 Unadjusted and adjusted linear regression analyses with flow-mediated vasodilation (ΔFMD) as the dependent variable

From: Rosuvastatin improves endothelial function in patients with inflammatory joint diseases, longitudinal associations with atherosclerosis and arteriosclerosis: results from the RORA-AS statin intervention study

  

Unadjusted analyses

Adjusted analysesa

 

β (95 % CI)

p value

β (95 % CI)

p value

Age

−0.07 (−0.14, 0.01)

0.09

 

Gender

0.38 (−0.89, 1.66)

0.55

 

bDMARDs

−1.07 (−2.31, 0.18)

0.09

 

CRP

Baseline

−0.01 (−0.18, 0.16)

0.92

−0.02 (−0.18, 0.15)

0.86

Change

0.04 (−0.01, 0.09)

0.13

0.05 (−0.01, 0.10)

0.08

ESR

Baseline

−0.01 (−0.07, 0.05)

0.83

0.01 (−0.06, 0.08)

0.76

Change

0.04 (−0.02, 0.09)

0.18

0.04 (−0.01, 0.09)

0.15

DAS28

Baseline

0.24 (−0.82, 1.29)

0.66

0.29 (−0.73, 1.31)

0.57

Change

0.02 (−1.23, 1.27)

0.98

−0.25 (−1.43, 0.93)

0.67

ASDAS

Baseline

−0.01 (−0.40, 0.38)

0.96

0.08 (−0.53, 0.68)

0.78

Change

0.14 (−0.31, 0.58)

0.52

0.14 (−0.52, 0.81)

0.63

LDL-c

Baseline

0.01 (0.62, 0.63)

0.98

−0.13 (−0.75, 0.50)

0.69

Change

−0.17 (−0.91, 0.57)

0.65

−0.06 (−0.80, 0.68)

0.87

HDL-c

Baseline

−0.54 (−1.78, 0.70)

0.39

−0.26 (−1.70, 1.17)

0.72

Change

−1.33 (−3.18, 0.52)

0.16

−1.43 (−3.28, 0.42)

0.13

AIx, change

−0.09 (−0.18, 0.01)

0.06

−0.09 (−0.18, 0.00)

< 0.05

aPWV, change

−0.07 (−0.58, 0.43)

0.78

−0.14 (−0.66, 0.38)

0.59

CP height, change

−3.51 (−5.28, −1.73)

< 0.001

−3.10 (−4.95, −1.25)

0.001

c-IMT, change

3.55 (−4.51, 11.62)

0.38

3.96 (−4.77, 12.70)

0.37

Rosuvastatin dose

0.02 (−0.03, 0.07)

0.48

0.01 (−0.04, 0.06)

0.76

  1. bDMARDs biologic disease-modifying antirheumatic drugs, CRP C-reactive protein, ESR erythrocyte sedimentation rate, DAS28 disease activity score in 28 joints, ASDAS ankylosing spondylitis disease activity score, LDL-c low-density lipoprotein cholesterol, HDL-c high-density lipoprotein cholesterol, AIx augmentation index, aPWV aortic pulse wave velocity, CP carotid plaque, c-IMT carotid intima-media thickness
  2. aAdjusted for age, gender and use of bDMARDs