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Table 2 Spearman’s correlation coefficients of pretreatment clinical variables with 14-3-3η

From: Serum 14-3-3η level is associated with severity and clinical outcomes of rheumatoid arthritis, and its pretreatment level is predictive of DAS28 remission with tocilizumab

Variables

DAS28-ESR

SDAI

CDAI

HAQ

SHS

JSN score

Erosion score

TJC28

SJC28

14-3-3η

CRP

ESR

DAS28-ESR

            

SDAI

0.91a

           

CDAI

0.89a

0.99a

          

HAQ

0.59a

0.54a

0.53a

         

SHS

0.34a

0.28b

0.27b

0.43a

        

JSN score

0.33a

0.28b

0.27b

0.41a

0.98a

       

Erosion score

0.32a

0.24b

0.23b

0.43a

0.97a

0.91a

      

TJC28

0.80a

0.86a

0.89a

0.45a

0.19c

0.19c

0.16

     

SJC28

0.73a

0.84a

0.84a

0.33a

0.35a

0.33a

0.28b

0.69a

    

14-3-3η

0.29a

0.24b

0.25d

0.05

0.16

0.18c

0.16

0.21c

0.26b

   

CRP

0.58a

0.49a

0.36a

0.34a

0.32a

0.32a

0.32a

0.22b

0.29a

0.20c

  

ESR

0.64a

0.37a

0.29a

0.34a

0.33a

0.32a

0.32a

0.18c

0.29b

0.27b

0.75 a

 
  1. Abbreviations: CDAI Clinical Disease Activity Index, CRP C-reactive protein, DAS28-ESR Disease Activity Score in 28 joints with erythrocyte sedimentation rate, ESR erythrocyte sedimentation rate, HAQ Health Assessment Questionnaire, JSN joint space narrowing, SDAI Simple Disease Activity Index, SHS Sharp/van der Heijde score, SJC28 28-joint swollen joint count, TJC28 28-joint tender joint count
  2. a p < 0.0001
  3. b p < 0.01
  4. c p < 0.05
  5. d p < 0.001