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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: CCR6+ Th cell populations distinguish ACPA positive from ACPA negative rheumatoid arthritis

Fig. 3

Differences in CCR6CD4+ T cell subpopulations and Tregs between ACPA+ patients and matched ACPA patients. a Gating strategy for the identification of peripheral blood Th1, Th2 and CCR4/CXCR3 DP cell subpopulations. CCR6 cells were gated on CD4+CD45RO+CD25 T cells. b Gating strategy to identify Treg (CD25hiFOXP3+) cells within the memory CD4+ T cell population. Cells were gated on the total lymphocyte population. c Proportions of the indicated CD4+ T cell subpopulations within the total memory CD4+ T cell population of 27 ACPA+ and 27 ACPA patients with RA. For statistical analysis Wilcoxon matched-pairs signed-ranks test was performed (* = p < 0.05).

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