European | Polynesian | Meta-analysis | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Gene, SNP, minor allele | MAF case | MAF control | OR (95 % CI) | P | MAF case | MAF control | OR (95 % CI) | P | OR (StdErr) | P |
NLRP3, rs10754558, G | 0.408 | 0.418 | 0.95 (0.87–1.04) | 0.25 | 0.459 | 0.434 | 1.07 (0.91–1.24) | 0.42 | 0.96 (0.036) | 0.44 |
NLRP3, rs35829419, A | 0.046 | 0.047 | 0.88 (0.71–1.07) | 0.20 | 0.004 | 0.012 | 0.58 (0.20–1.53) | 0.29 | 0.87 (0.098) | 0.15 |
NLRP3, rs7512998, C | 0.170 | 0.160 | 1.09 (0.94–1.27) | 0.25 | 0.033 | 0.045 | 1.03 (0.67–1.60) | 0.88 | 1.08 (0.075) | 0.29 |
CARD8, rs2043211, T | 0.338 | 0.321 | 1.11 (1.01–1.22) | 0.023 | 0.499 | 0.439 | 1.15 (0.98–1.35) | 0.078 | 1.12 (0.042) | 0.007 |
IL1B, rs1143623, G | 0.278 | 0.266 | 1.09 (0.99–1.20) | 0.066 | 0.532 | 0.481 | 1.14 (0.98–1.33) | 0.098 | 1.10 (0.042) | 0.020 |
TLR2, rs4696480, T | 0.495 | 0.499 | 1.02 (0.93–1.11) | 0.68 | 0.482 | 0.490 | 0.98 (0.84–1.15) | 0.84 | 1.01 (0.036) | 0.74 |
CD14, rs2569190, A | 0.496 | 0.475 | 1.08 (0.99–1.18) | 0.070 | 0.576 | 0.542 | 1.07 (0.92–1.26) | 0.37 | 1.08 (0.036) | 0.036 |
MYD88, rs6853, G | 0.112 | 0.120 | 0.88 (0.77–1.00) | 0.059 | 0.026 | 0.028 | 1.18 (0.71–1.98) | 0.52 | 0.90 (0.068) | 0.11 |
P2RX7, rs17525809, C | 0.071 | 0.068 | 1.09 (0.92–1.29) | 0.30 | 0.056 | 0.068 | 0.78 (0.56–1.08) | 0.13 | 1.01 (0.080) | 0.87 |
DAPK1, rs4878104, T | 0.358 | 0.353 | 1.02 (0.93–1.11) | 0.72 | 0.701 | 0.622 | 1.13 (0.96–1.34) | 0.14 | 1.05 (0.044) | 0.32 |
TNXIP, rs7212, G | 0.050 | 0.041 | 1.27 (1.04–1.55) | 0.020 | 0.191 | 0.175 | 1.00 (0.82–1.22) | 0.98 | 1.13 (0.071) | 0.091 |