| |
rOA progression
|
ROM progression
|
THR
|
Disability progression
|
Any progression
|
|---|
|
Osteophytes
|
(n = 411 hips)
|
(n = 404 hips)
|
(n = 12 hips)
|
(n = 445 participants)
|
(n = 1406 participants)
|
|---|
|
Any site
|
0.99 (0.77, 1.29)
|
1.51 (1.19, 1.92)*
|
1.87 (0.40, 8.83)
|
1.05 (0.81, 1.36)
|
0.84 (0.72, 0.97)
|
|
Medial
| | | | | |
|
Any site
|
2.99 (1.93, 4.64)*
|
1.27 (0.89, 1.81)
|
17.4 (4.80, 63.1)*
|
1.28 (0.89, 1.84)
|
1.39 (1.05, 1.83)
|
|
Any acetabular
|
2.80 (1.34, 5.83)
|
1.58 (1.04, 2.42)
|
5.33 (1.01, 28.1)
|
1.39 (0.78, 2.50)
|
1.40 (0.98, 2.02)
|
|
Any femoral
|
2.63 (1.52, 4.54)*
|
0.72 (0.46, 1.12)
|
13.5 (3.23, 56.5)*
|
1.66 (0.96, 2.85)
|
1.19 (0.85, 1.68)
|
|
Both acetabular and femoral
|
2.55 (0.52, 12.6)
|
0.41 (0.20, 0.84)
|
30.3 (4.25, 216)*
|
1.40 (0.51, 3.85)
|
0.97 (0.49, 1.95)
|
|
Lateral
| | | | | |
|
Any site
|
0.95 (0.73, 1.23)
|
1.40 (1.11, 1.77)†a
|
1.15 (0.30, 4.44)
|
1.04 (0.80, 1.34)
|
0.82 (0.71, 0.95)
|
|
Any acetabular
|
0.94 (0.71, 1.24)
|
1.45 (1.15, 1.84)*†b
|
1.67 (0.48, 5.78)
|
0.99 (0.78, 1.26)
|
0.84 (0.71, 1.00)
|
|
Any femoral
|
1.43 (1.03, 1.97)
|
0.95 (0.72, 1.26)†c
|
4.09 (1.28, 13.1)
|
1.18 (0.88, 1.58)
|
1.11 (0.92, 1.33)†d
|
|
Both acetabular and femoral
|
1.65 (1.12, 2.41)
|
1.00 (0.71, 1.39)
|
4.08 (1.24, 13.4)
|
1.19 (0.85, 1.67)
|
1.21 (0.97, 1.50)†e
|
- All models adjusted for age, gender, race, prior hip injury, body mass index, education, smoking and follow-up time; the radiographic osteoarthritis (rOA) outcome was additionally adjusted for baseline Kellgren–Lawrence grade, while the disability outcome was adjusted also for the Center for Epidemiologic Studies depression scale. *Statistically significant after Bonferroni p value adjustment. †Significant interactions by race. †aFor AAs aOR = 0.99, 95 % CI (0.64, 1.53), for Caucasians aOR 1.65, 95 % CI (1.25, 2.17), interaction p = 0.038. †bFor AAs aOR = 1.10, 95 % CI (0.72, 1.68), for Caucasians aOR = 1.65, 95 % CI (1.25, 2.19), interaction p = 0.091. †cFor AAs aOR = 0.58, 95 % CI (0.34, 0.98), for Caucasians aOR = 1.16, 95 % CI (0.83, 1.61), interaction p = 0.015. †dFor AAs aOR = 0.83, 95 % CI (0.58, 1.19), for Caucasians aOR = 1.23, 95 % CI (0.99, 1.52), interaction p = 0.056. †eFor AAs aOR = 0.87, 95 % CI (0.59, 1.28), for Caucasians aOR = 1.33, 95 % CI (1.01, 1.76), interaction p = 0.067 ROM range of motion, THR total hip replacement
