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Table 5 Adjusted odds ratios (aORs) for associations between patterns of osteophytes and progression

From: Racial differences in associations between baseline patterns of radiographic osteoarthritis and multiple definitions of progression of hip osteoarthritis: the Johnston County Osteoarthritis Project

  rOA progression ROM progression THR Disability progression Any progression
Osteophytes (n = 411 hips) (n = 404 hips) (n = 12 hips) (n = 445 participants) (n = 1406 participants)
Any site 0.99 (0.77, 1.29) 1.51 (1.19, 1.92)* 1.87 (0.40, 8.83) 1.05 (0.81, 1.36) 0.84 (0.72, 0.97)
Medial      
 Any site 2.99 (1.93, 4.64)* 1.27 (0.89, 1.81) 17.4 (4.80, 63.1)* 1.28 (0.89, 1.84) 1.39 (1.05, 1.83)
 Any acetabular 2.80 (1.34, 5.83) 1.58 (1.04, 2.42) 5.33 (1.01, 28.1) 1.39 (0.78, 2.50) 1.40 (0.98, 2.02)
 Any femoral 2.63 (1.52, 4.54)* 0.72 (0.46, 1.12) 13.5 (3.23, 56.5)* 1.66 (0.96, 2.85) 1.19 (0.85, 1.68)
 Both acetabular and femoral 2.55 (0.52, 12.6) 0.41 (0.20, 0.84) 30.3 (4.25, 216)* 1.40 (0.51, 3.85) 0.97 (0.49, 1.95)
Lateral      
 Any site 0.95 (0.73, 1.23) 1.40 (1.11, 1.77)†a 1.15 (0.30, 4.44) 1.04 (0.80, 1.34) 0.82 (0.71, 0.95)
 Any acetabular 0.94 (0.71, 1.24) 1.45 (1.15, 1.84)*†b 1.67 (0.48, 5.78) 0.99 (0.78, 1.26) 0.84 (0.71, 1.00)
 Any femoral 1.43 (1.03, 1.97) 0.95 (0.72, 1.26)†c 4.09 (1.28, 13.1) 1.18 (0.88, 1.58) 1.11 (0.92, 1.33)†d
 Both acetabular and femoral 1.65 (1.12, 2.41) 1.00 (0.71, 1.39) 4.08 (1.24, 13.4) 1.19 (0.85, 1.67) 1.21 (0.97, 1.50)†e
  1. All models adjusted for age, gender, race, prior hip injury, body mass index, education, smoking and follow-up time; the radiographic osteoarthritis (rOA) outcome was additionally adjusted for baseline Kellgren–Lawrence grade, while the disability outcome was adjusted also for the Center for Epidemiologic Studies depression scale. *Statistically significant after Bonferroni p value adjustment. Significant interactions by race. †aFor AAs aOR = 0.99, 95 % CI (0.64, 1.53), for Caucasians aOR 1.65, 95 % CI (1.25, 2.17), interaction p = 0.038. †bFor AAs aOR = 1.10, 95 % CI (0.72, 1.68), for Caucasians aOR = 1.65, 95 % CI (1.25, 2.19), interaction p = 0.091. †cFor AAs aOR = 0.58, 95 % CI (0.34, 0.98), for Caucasians aOR = 1.16, 95 % CI (0.83, 1.61), interaction p = 0.015. †dFor AAs aOR = 0.83, 95 % CI (0.58, 1.19), for Caucasians aOR = 1.23, 95 % CI (0.99, 1.52), interaction p = 0.056. †eFor AAs aOR = 0.87, 95 % CI (0.59, 1.28), for Caucasians aOR = 1.33, 95 % CI (1.01, 1.76), interaction p = 0.067 ROM range of motion, THR total hip replacement