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Table 1 Patient characteristics, baseline laboratory parameters, circulating endothelial cell counts and treatment in 20 children with systemic vasculitis

From: Impaired function of endothelial progenitor cells in children with primary systemic vasculitis

Demographic data Active PSV (n = 15) Inactive PSV (n = 5)
Median age, years (range) 12 (7–16.5) 12 (9–11.6)
Sex M/F 5 M:10 F 1 M:4 F
Classification n = 8 PAN; n = 4 GPA; n = 1 EGPA; n = 1 KD; n = 1 unclassified SV n = 4 GPA; n = 1 Behçet’s disease
ESR, mm/h (median, range) 73 (11–137) 3 (3–37)
CRP, mg/L (median, range) 18.5 (5–270) 5 (5–16)
CEC count, cells/ml (median, range) 88 (8–420) 16 (0–40)
Treatment (n)   
Cyclophosphamide 5 2
Corticosteroids 11 3
MMF 1 2
Azathioprine 0 1
Colchicine 0 1
Rituximab 1 0
  1. Classification of the vasculitic syndromes was based on the recent EULAR/PRINTO/PRES classification criteria for pediatric vasculitis [19]. KD was identified based on five of six of the American Heart Criteria. Immunomagnetic bead extraction was used for enumeration of circulating endothelial cells (CEC). Treatments summarised were received at any point of the patients’ disease course. PAN polyarteritis nodosa, KD Kawasaki disease, GPA granulomatosis with polyangiitis, EGPA eosinophilic granulomatosis with polyangiitis, ESR erythrocyte sedimentation rate, CRP C-reactive protein, MMF mycophenolate mofetil