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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Antigen-induced arthritis in rats is associated with increased growth-associated protein 43–positive intraepidermal nerve fibres remote from the joint

Fig. 1

Joint swelling and pain-related behaviour. a The ipsilateral knee joint showed pronounced swelling in the acute state of antigen-induced arthritis (AIA) compared with baseline values obtained before induction of AIA. b Animals with acute AIA bore significantly less weight on the inflamed hind limb compared with baseline values. c Withdrawal thresholds for mechanical stimulation of the knee joint were significantly decreased in the acute state of AIA. d Withdrawal thresholds for monofilament stimulation of the paw pad decreased in animals with AIA, but the values did not reach statistical significance. Baseline values for acute and chronic AIA were pooled for the graphs, as there were no significant differences between the values in these two groups. **p < 0.01

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Arthritis Research & Therapy

ISSN: 1478-6362

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