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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Investigation of the cytokine response to NF-κB decoy oligonucleotide coated polysaccharide based nanoparticles in rheumatoid arthritis in vitro models

Fig. 6

Cellular uptake visualization of Alexa Fluor 488 tagged PSA-TMC coated with Texas Red labeled decoy ODNs in SW982 synovial sarcoma cells. Cells were incubated with tagged particles for 45 minutes at 37 °C, and then imaged using an inverted fluorescent microscope. When administered alone, decoy ODN do not register a large signal. However, when delivered using the PSA-TMC carrier system, both red and green signals are clearly seen. NP PSA-TMC nanoparticles, ODN oligonucleotide

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