Fig. 4From: Effects of tofacitinib monotherapy on patient-reported outcomes in a randomized phase 3 study of patients with active rheumatoid arthritis and inadequate responses to DMARDsTime to first sequential decrease from baseline. Interactive voice response system (IVRS) Patient Global Assessment of Disease Activity (PtGA) (a) and IVRS Patient Global Assessment of Pain (Pain) (b). A sequential decrease was defined as at least 2Â days of consecutive improvement in each measure. BID twice dailyBack to article page