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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA

Fig. 6

Polarized light picture of the proximal tibial epiphysis stained with hematoxylin and eosin (H&E) from rats assign to study group 6A to 6D. All three groups of medial meniscectomy (MM) rats had thicker subchondral bone plate (sbp), particularly the rats treated with zoledronate (Zol). Additionally, the calcified cartilage layer seemed to be better preserved in the Zol-treated group. The arrowhead indicates defects of the articular cartilage, and the green arrowhead indicates osteophytes

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