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Table 2 Zonal measurement of the cartilage volume and thickness at the medial tibial plateau

From: Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA

    

S T U D Y G R O U P S

 

Parameter

Unit

Zone

Sham

MM + veh

MM + Zol

MM + PTH

  

z1

0.12 ± 0.02

0.19 ± 0.06*

0.19 ± 0.06*

0.19 ± 0.06*

Cartilage

mm3

z2

0.20 ± 0.02

0.11 ± 0.04**

0.12 ± 0.03**

0.12 ± 0.06**

Volume

 

z3

0.19 ± 0.04

0.23 ± 0.04*

0.23 ± 0.05*

0.23 ± 0.06*

  

z1

0.14 ± 0.02

0.18 ± 0.06*

0.18 ± 0.04*

0.18 ± 0.07*

Cartilage

mm

z2

0.23 ± 0.02

0.15 ± 0.04**

0.15 ± 0.03**

0.15 ± 0.06**

Thickness

 

z3

0.23 ± 0.04

0.20 ± 0.03

0.21 ± 0.03

0.20 ± 0.05

  1. Sham, sham control group, MM + veh medial meniscectomy (MM) vehicle-treated group, MM + Zol MM + zoledronate group, MM + PTH MM + parathyroid hormone group
  2. * p < 0.05 or ** p < 0.001 relative to sham rats