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Table 1 Demographic and clinical characteristics of the patients with rheumatoid arthritis

From: PTGER4 gene variant rs76523431 is a candidate risk factor for radiological joint damage in rheumatoid arthritis patients: a genetic study of six cohorts

 

Cohort

Variable

HCSC-RAC

PEARL

PAZ

EAC

Wichita

NDB

Total patients, n

402

81

42

597

100

567

Total sets of X-rays, n

637

210

173

3143

353

567

Female sex, n (%)

304 (75.62)

62 (76.54)

26 (61.90)

402 (67.3)

70 (70.0)

444 (78.3)

Age at diagnosis, yr, mean (SD)

57.09 (13.61)

55.39 (17.33)

53.11 (14.77)

57.1 (15.6)

49.1 (11.6)

48.7 (12.7)

Year at RA diagnosis, range

1976–2011

2000–2011

1992–2004

1993–2006

1963–1999

1980–1999

RF positivity, n (%)

260 (64.68)

47 (58.02)

35 (83.33)

342 (57.6)a

ACPA positivity, n (%)

167 (47.18)b

38 (47.50)c

33 (78.57)

309 (52.8)d

96 (97.0)e

452 (79.7)

Radiographic follow-up, yr

15

5

10

7

15

NA

  1. ACPA anticitrullinated peptide antibodies, EAC Leiden Early Arthritis Clinic cohort, HCSC-RAC Hospital Clínico San Carlos rheumatoid arthritis cohort, NDB National Databank for Rheumatic Diseases cohort, PAZ Hospital Universitario de La Paz early arthritis cohort, PEARL Princesa Early Arthritis Register Longitudinal study cohort, RA rheumatoid arthritis, RF rheumatoid factor, SD standard deviation
  2. aRF status missing in three patients from the EAC cohort
  3. bACPA status missing in 60 patients from the HCSC-RAC cohort
  4. cACPA status missing in one patient from the PEARL cohort
  5. dACPA status missing in 12 patients from the EAC cohort
  6. eACPA status missing in one patients from the Wichita cohort