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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: A novel method to detect articular chondrocyte death during early stages of osteoarthritis using a non-invasive ApoPep-1 probe

Fig. 6

ApoPep-1 binds to grade II osteoarthritis (OA) cartilage. Joints were harvested and cryo-sectioned 2 weeks after sham operation or surgical destabilization of the medial meniscus. ApoPep-1 was injected intravenously before harvest. a Strong signals of ApoPep-1 and TUNEL both appear in grade II OA joints, but not in sham-operated joints. b ApoPep-1 and histone H1 appear in OA cartilage, but not sham-operated cartilage. Scale bar 50 μm. DAPI 4′, 6′ -diamidino-2-phenylindole

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