Skip to main content

Table 4 ILD-related hospitalization rate per 1000 PY, unadjusted

From: Incidence and complications of interstitial lung disease in users of tocilizumab, rituximab, abatacept and anti-tumor necrosis factor α agents, a retrospective cohort study

Cohort

Specific definition

Sensitive definition

Events (total PY)

Events (total PY)

Rate (95 % CI)

Rate (95 % CI)

All eligible

4 (61)

42 (329)

65.8 (17.9–68.4)

127.7 (92.0–172.6)

Anti-TNFα agents

1 (28)

17 (152)

35.2 (0.9–195.9)

111.9 (65.2–179.1)

Etanercept

1

6 (33)

261.5 (6.6–1456.7)

180.6 (66.3–393.1)

Adalimumab

0

3 (45)

0.0 (0.0–253.9)

67.4 (13.9–197.0)

Infliximab

0

4 (15)

0.0 (0.0–1445.4)

262.5 (71.5–672.2)

Certolizumab

0

2 (28)

0.0 (0.0–761.4)

72.2 (8.7–260.7)

Golimumab

0

2 (31)

0.0 (0.0–439.8)

63.9 (7.7–230.8)

Tocilizumab

1

2 (36)

128.7 (3.3–717.1)

55.6 (6.7–200.7)

Rituximab

1 (13)

16 (68)

78.8 (95 % CI 2.0–439.1)

234.2 (95 % CI 133.8–380.3)

Abatacept

1

7 (73)

83.8 (95 % CI 2.1–467.0)

96.5 (95 % CI 38.8–198.7)

  1. ILD interstitial lung disease, PY person-year, CI confidence interval, TNFα tumor necrosis factor alpha