|
Visits
|
University/college degree
|
Outcome values above the median
|
|---|
|
No
|
Yes
|
Risk ratio, crude (95 % CI)
|
Risk ratio* (95 % CI)
|
|---|
|
DAS28
|
|
3 months
|
No
|
860 (74.7)
|
291 (25.3)
|
1.0 ref.
|
1.0 ref.
|
|
Yes
|
889 (76.6)
|
272 (23.4)
|
0.95 (0.86 to 1.05)
|
0.99 (0.90 to 1.09)
|
|
6 months
|
No
|
762 (77.0)
|
227 (23.0)
|
1.0 ref.
|
1.0 ref.
|
|
Yes
|
776 (78.4)
|
214 (21.6)
|
0.96 (0.86 to 1.07)
|
1.01 (0.90 to 1.13)
|
|
1 year
|
No
|
975 (75.6)
|
314 (24.4)
|
1.0 ref.
|
1.0 ref.
|
|
Yes
|
1007 (77.4)
|
294 (22.6)
|
0.95 (0.87 to 1.04)
|
0.98 (0.89 to 1.08)
|
|
VAS-pain
|
|
3 months
|
No
|
817 (72.1)
|
316 (27.9)
|
1.0 ref.
|
1.0 ref.
|
|
Yes
|
948 (79.3)
|
247 (20.7)
|
0.82 (0.74 to 0.91)
|
0.88 (0.79 to 0.98)
|
|
6 months
|
No
|
751 (75.3)
|
246 (24.7)
|
1.0 ref.
|
1.0 ref.
|
|
Yes
|
804 (80.3)
|
197 (19.7)
|
0.86 (0.77 to 0.96)
|
0.93 (0.82 to 1.05)
|
|
1 year
|
No
|
947 (72.9)
|
352 (27.1)
|
1.0 ref.
|
1.0 ref.
|
|
Yes
|
1058 (80.0)
|
264 (20.0)
|
0.81 (0.73 to 0.90)
|
0.85 (0.76 to 0.94)
|
|
HAQ
|
|
3 months
|
No
|
743 (71.8)
|
292 (28.2)
|
1.0 ref.
|
1.0 ref.
|
|
Yes
|
986 (79.1)
|
261 (20.9)
|
0.83 (0.75 to 0.91)
|
0.90 (0.82 to 0.99)
|
|
6 months
|
No
|
689 (75.1)
|
229 (24.9)
|
1.0 ref.
|
1.0 ref.
|
|
Yes
|
827 (80.0)
|
207 (20.0)
|
0.87 (0.78 to 0.97)
|
0.93 (0.83 to 1.04)
|
|
1 year
|
No
|
817 (72.9)
|
304 (27.1)
|
1.0 ref.
|
1.0 ref.
|
|
Yes
|
1130 (79.5)
|
292 (20.5)
|
0.84 (0.77 to 0.92)
|
0.90 (0.82 to 0.98)
|
- Risk ratio crude: poisson regression estimates without adjustment. Risk ratio*: poisson regression estimates adjusted for age at diagnosis, gender, alcohol assumption, pack-years of smoking, body mass index, and baseline outcome values. DAS28 disease activity in 29 joints, VAS visual analog scale
