A subset of CD163+ macrophages displays mixed polarizations in discoid lupus skin

Table 2 Gene set enrichment analysis of differentially expressed genes in DLE lesional and normal skin

Name	Size	ES	NES	P value	FDR q value
IFN-γ-stimulated (M1) macrophages upregulated	113	0.92	1.25	0.02	0.02
IFN-γ stimulated (M1) macrophages downregulated	16	−0.55	−1.24	0.25	0.25
IL-4 stimulated (M2) macrophages upregulated	26	0.39	0.97	0.49	0.49
IL-4 stimulated (M2) macrophages downregulated	1	0.95	1.11	0.27	0.27

Abbreviations: DLE discoid lupus erythematosus, ES enrichment score, FDR false discovery rate, IFN-γ interferon-gamma, IL-4 interleukin-4, NES normalized enrichment score

ISSN: 1478-6362