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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation

Fig. 4

Effects of Citral on renal infiltration by monocytes/macrophages and T cells and NF-κB activation in the kidney of a mouse model. Detection of CD3+ T cells (a-c) and F4/80+ monocytes/macrophages (d-f) by immunohistochemistry. Original magnification × 400. Arrows indicate positively stained cells. Scoring of CD3+ cells (g and h) or F4/80+ cells (i and j) in the glomerulus (g and i) or interstitium (h and j). k Nuclear NF-κBp65 activity. Bars show mean ± standard error of the mean for 7 mice per group; ***p <0.005, ns not significant. ALSN accelerated and severe lupus nephritis

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