Fig. 7From: Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activationEffect of Citral on renal levels of superoxide anion, cytoplasmic NAD(P)H oxidase subunit p47phox and cyclooxygenase-2 (COX-2), nuclear nuclear factor E2-related factor 2 (Nrf2), and serum prostaglandin E2 (PGE2) in mouse model. a Reactive oxygen species levels in renal tissues expressed as reactive luminescence units (RLU)/15 min/mg dry weight. b Representative western blots for cytosolic levels of p47phox and COX-2, with β-actin as the loading control. c and d Semiquantitative analysis of the p47phox/β-actin ratio (c) and the COX-2/β-actin ratio (d). e Serum PGE2 levels measured by ELISA. f Representative western blots for nuclear levels of Nrf2. with Lamin A as the loading control. g Semiquantitative analysis of the Nrf2/Lamin A ratio. Bars show mean ± standard error of the mean for 7 mice per group; *p <0.05, **p <0.01, and ***p <0.005. ASLN accelerated and severe lupus nephritisBack to article page